Preparation of DNC Solid Dispersion by a Mechanochemical Method with Glycyrrhizic Acid and Polyvinylpyrrolidone to Enhance Bioavailability and Activity

To exploit aqueous-soluble formulation and improve the anticoccidial activity of 4,4′-dinitrocarbanilide (DNC, active component of nicarbazin), this paper prepared DNC/GA/PVP K30 solid dispersion (SD) with glycyrrhizic acid (GA) and polyvinylpyrrolidone (PVP) K30 by a mechanical ball milling method...

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Bibliographic Details
Main Authors: Min Lu, Wei Wei, Wenhao Xu, Nikolay E. Polyakov, Alexandr V. Dushkin, Weike Su
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Polymers
Subjects:
Online Access:https://www.mdpi.com/2073-4360/14/10/2037