Furosemide exacerbated the impairment of renal function, oxygenation and medullary damage in a rat model of renal ischemia/reperfusion induced AKI

Furosemide exacerbated the impairment of renal function, oxygenation and medullary damage in a rat model of renal ischemia/reperfusion induced AKI

Abstract Background Perioperative acute kidney injury (AKI) caused by ischemia–reperfusion (IR) is a significant contributor to mortality and morbidity after major surgery. Furosemide is commonly used in postoperative patients to promote diuresis and reduce tissue edema. However, the effects of furo...

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Bibliographic Details
Main Authors: Olcay Dilken, Can Ince, Aysegul Kapucu, Paul M. Heeman, Bülent Ergin
Format: Article
Language:English
Published: SpringerOpen 2023-05-01
Series:Intensive Care Medicine Experimental
Subjects:
Acute kidney injury
Renal failure
Furosemide
Urine output
Creatinine
Oxygenation
Online Access:https://doi.org/10.1186/s40635-023-00509-3

Internet

https://doi.org/10.1186/s40635-023-00509-3

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