Use of Imaging Techniques to Illuminate Dynamics of Hematopoietic Stem Cells and Their Niches
Continuous generation of blood cells over an organism's lifetime is supported by hematopoietic stem/progenitor cells (HSPCs) capable of producing all hematopoietic cell subtypes. Adult mammalian HSPCs are localized to bone marrow and regulated by their neighboring microenvironment, or “niche.”...
Main Authors: | , |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2017-06-01
|
Series: | Frontiers in Cell and Developmental Biology |
Subjects: | |
Online Access: | http://journal.frontiersin.org/article/10.3389/fcell.2017.00062/full |