Spatial Distribution of Immune Cells in Head and Neck Squamous Cell Carcinomas

Spatial Distribution of Immune Cells in Head and Neck Squamous Cell Carcinomas

BackgroundHead and neck squamous cell carcinomas (HNSCCs) have a very moderate response rate to immune checkpoint inhibitor (ICI) treatment compared to other cancer types. Lacking predictive markers for treatment response, we analyzed the immune status of HNSCC and assessed the spatial distribution...

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Bibliographic Details
Main Authors: Christian Idel, Julika Ribbat-Idel, Luise Klapper, Rosemarie Krupar, Karl-Ludwig Bruchhage, Eva Dreyer, Dirk Rades, Christina Polasky, Anne Offermann, Jutta Kirfel, Sven Perner, Barbara Wollenberg
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Oncology
Subjects:
HNSCC
immune landscape
spatial distribution
TGF-β
PD-L1
PD-1
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.712788/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.712788/full

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