Identification and Regulation of TCRαβ+CD8αα+ Intraepithelial Lymphocytes in Murine Oral Mucosa

TCRαβ+CD8αα+ intraepithelial lymphocytes (IELs) are abundant in gastrointestinal (GI) tract and play an important role in regulation of mucosal immunity and tolerance in the gut. However, it is unknown whether TCRαβ+CD8αα+ IELs exist in the oral mucosa and if yes, what controls their development. We...

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Bibliographic Details
Main Authors: Ruiqing Wu, Dunfang Zhang, Peter Zanvit, Wenwen Jin, Hao Wang, WanJun Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.01702/full