Gut Antibody Deficiency in a Mouse Model of CVID Results in Spontaneous Development of a Gluten-Sensitive Enteropathy

Gut Antibody Deficiency in a Mouse Model of CVID Results in Spontaneous Development of a Gluten-Sensitive Enteropathy

Primary immunodeficiencies are heritable disorders of immune function. CD19 is a B cell co-receptor important for B cell development, and CD19 deficiency is a known genetic risk factor for a rare form of primary immunodeficiency known as “common variable immunodeficiency” (CVID); an antibody deficie...

Full description

Bibliographic Details
Main Authors: Ahmed Dawood Mohammed, Md. A. Wadud Khan, Ioulia Chatzistamou, Douja Chamseddine, Katie Williams-Kang, Mason Perry, Reilly Enos, Angela Murphy, Gregorio Gomez, Ahmed Aladhami, Carole A. Oskeritzian, Amy Jolly, Yan Chang, Shuqian He, Zui Pan, Jason L. Kubinak
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Immunology
Subjects:
CVID
primary immunodeficiency
dysbiosis
CVID enteropathy
gluten sensitivity
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02484/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.02484/full

Similar Items