Extracellular Vesicle Mediated Tumor-Stromal Crosstalk Within an Engineered Lung Cancer Model

Extracellular Vesicle Mediated Tumor-Stromal Crosstalk Within an Engineered Lung Cancer Model

Tumor-stromal interactions within the tumor microenvironment (TME) influence lung cancer progression and response to therapeutic interventions, yet traditional in vitro studies fail to replicate the complexity of these interactions. Herein, we developed three-dimensional (3D) lung tumor models that...

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Bibliographic Details
Main Authors: Kayla F. Goliwas, Hannah M. Ashraf, Anthony M. Wood, Yong Wang, Kenneth P. Hough, Sandeep Bodduluri, Mohammad Athar, Joel L. Berry, Selvarangan Ponnazhagan, Victor J. Thannickal, Jessy S. Deshane
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Oncology
Subjects:
tumor-stromal crosstalk
extracellular vesicles
3D tissue models
lung carcinoma
tumor-immune regulation
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.654922/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2021.654922/full

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