DAPL1 prevents epithelial–mesenchymal transition in the retinal pigment epithelium and experimental proliferative vitreoretinopathy

DAPL1 prevents epithelial–mesenchymal transition in the retinal pigment epithelium and experimental proliferative vitreoretinopathy

Abstract Epithelial–mesenchymal transition (EMT) of the retinal pigment epithelium (RPE) is a hallmark of the pathogenesis of proliferative vitreoretinopathy (PVR) that can lead to severe vision loss. Nevertheless, the precise regulatory mechanisms underlying the pathogenesis of PVR remain largely u...

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Bibliographic Details
Main Authors: Xiaoyin Ma, Shuxian Han, Youjia Liu, Yu Chen, Pingping Li, Xiaoyan Liu, Lifu Chang, Ying-ao Chen, Feng Chen, Qiang Hou, Ling Hou
Format: Article
Language:English
Published: Nature Publishing Group 2023-02-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-023-05693-4

Internet

https://doi.org/10.1038/s41419-023-05693-4

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