Evolution of the primate APOBEC3A cytidine deaminase gene and identification of related coding regions.

Evolution of the primate APOBEC3A cytidine deaminase gene and identification of related coding regions.

The APOBEC3 gene cluster encodes six cytidine deaminases (A3A-C, A3DE, A3F-H) with single stranded DNA (ssDNA) substrate specificity. For the moment A3A is the only enzyme that can initiate catabolism of both mitochondrial and nuclear DNA. Human A3A expression is initiated from two different methion...

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Bibliographic Details
Main Authors: Michel Henry, Christophe Terzian, Martine Peeters, Simon Wain-Hobson, Jean-Pierre Vartanian
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3260193?pdf=render

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http://europepmc.org/articles/PMC3260193?pdf=render

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