Novel Phosphonium Dye TDV1 as a Potential Fluorescent Probe to Monitor DNA Interactions with Lysozyme Amyloid Fibrils

The applicability of the novel cationic phosphonium dye TDV1 to monitor the complexation between DNA and pathologically aggregated proteins, amyloid fibrils, was tested using the optical spectroscopy and molecular docking techniques. TDV1 has been found to be highly emissive in buffer solution and i...

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Bibliographic Details
Main Authors: Olga Zhytniakivska, Uliana Tarabara, Kateryna Vus, Valeriya Trusova, Galyna Gorbenko, Nikolai Gadjev, Todor Deligeorgiev
Format: Article
Language:English
Published: V.N. Karazin Kharkiv National University Publishing 2019-07-01
Series:East European Journal of Physics
Subjects:
Online Access:https://periodicals.karazin.ua/eejp/article/view/13481