Targeting CREB in Cancer Therapy: A Key Candidate or One of Many? An Update

Intratumor heterogeneity (ITH) is considered the major disorienting factor in cancer treatment. As a result of stochastic genetic and epigenetic alterations, the appearance of a branched evolutionary shape confers tumor plasticity, causing relapse and unfavorable clinical prognosis. The growing evid...

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Bibliographic Details
Main Authors: Luigi Sapio, Alessia Salzillo, Angela Ragone, Michela Illiano, Annamaria Spina, Silvio Naviglio
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/12/11/3166