Let-7 as biomarker, prognostic indicator, and therapy for precision medicine in cancer

Let-7 as biomarker, prognostic indicator, and therapy for precision medicine in cancer

Abstract Abnormal regulation and expression of microRNAs (miRNAs) has been documented in various diseases including cancer. The miRNA let-7 (MIRLET7) family controls developmental timing and differentiation. Let-7 loss contributes to carcinogenesis via an increase in its target oncogenes and stemnes...

Full description

Bibliographic Details
Main Authors: Evgeny Chirshev, Kerby C. Oberg, Yevgeniya J. Ioffe, Juli J. Unternaehrer
Format: Article
Language:English
Published: Wiley 2019-08-01
Series:Clinical and Translational Medicine
Subjects:
microRNA
Cancer
Gene regulation
Biomarker
Therapeutics
Tumor suppressor
Online Access:http://link.springer.com/article/10.1186/s40169-019-0240-y

Internet

http://link.springer.com/article/10.1186/s40169-019-0240-y

Similar Items