MiR-125b-5p alleviates pulmonary fibrosis by inhibiting TGFβ1-mediated epithelial-mesenchymal transition via targeting BAK1

MiR-125b-5p alleviates pulmonary fibrosis by inhibiting TGFβ1-mediated epithelial-mesenchymal transition via targeting BAK1

Abstract This study explores the role and potential mechanisms of microRNA-125b-5p (miR-125b-5p) in pulmonary fibrosis (PF). PF is a typical outcome of many chronic lung diseases, with poor prognosis and the lack of appropriate medical treatment because PF’s molecular mechanisms remain poorly unders...

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Bibliographic Details
Main Authors: Shuang Zhou, Wenzhao Cheng, Yifei Liu, Hongzhi Gao, Liying Yu, Yiming Zeng
Format: Article
Language:English
Published: BMC 2024-10-01
Series:Respiratory Research
Subjects:
MiR-125b-5p
BAK1
Epithelial‑mesenchymal transition
Pulmonary fibrosis
TGF-β1
Online Access:https://doi.org/10.1186/s12931-024-03011-w

Internet

https://doi.org/10.1186/s12931-024-03011-w

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