The contribution of oligodendrocytes and oligodendrocyte progenitor cells to central nervous system repair in multiple sclerosis: perspectives for remyelination therapeutic strategies

The contribution of oligodendrocytes and oligodendrocyte progenitor cells to central nervous system repair in multiple sclerosis: perspectives for remyelination therapeutic strategies

Oligodencrocytes (OLs) are the main glial cells of the central nervous system involved in myelination of axons. In multiple sclerosis (MS), there is an imbalance between demyelination and remyelination processes, the last one performed by oligodendrocyte progenitor cells (OPCs) and OLs, resulting in...

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Bibliographic Details
Main Author: Adriana Octaviana Dulamea
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2017-01-01
Series:Neural Regeneration Research
Subjects:
multiple sclerosis; oligodencrocytes; oligodendrocyte progenitor cells; demyelination; remyelination; semaphorin; basic helix-loop-helix transcription factor oligodendrocyte transcription factor 2; leucin-rich repeat and immunoglobulin-like-domain-containing nogo receptor-interacting protein 1; canonical Notch signaling; endocrine receptors
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2017;volume=12;issue=12;spage=1939;epage=1944;aulast=Dulamea

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2017;volume=12;issue=12;spage=1939;epage=1944;aulast=Dulamea

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