Laboratory biomarkers of an effective antitumor immune response. Clinical significance.

The modern checkpoint inhibitors block the programmed death-1 receptor and its ligand, cytotoxic T-lymphocyte-associated antigen 4 on tumor cells and lymphocytes, that induces cytotoxic reactions. Nowadays, there are no approved clinical and laboratory predictor markers of immune therapy efficacy, w...

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Bibliographic Details
Main Authors: A.M. Malkova, V.V. Sharoyko, N.V. Zhukova, A.R. Gubal, R.V. Orlova
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Cancer Treatment and Research Communications
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2468294221001854