Laboratory biomarkers of an effective antitumor immune response. Clinical significance.
The modern checkpoint inhibitors block the programmed death-1 receptor and its ligand, cytotoxic T-lymphocyte-associated antigen 4 on tumor cells and lymphocytes, that induces cytotoxic reactions. Nowadays, there are no approved clinical and laboratory predictor markers of immune therapy efficacy, w...
Main Authors: | A.M. Malkova, V.V. Sharoyko, N.V. Zhukova, A.R. Gubal, R.V. Orlova |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2021-01-01
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Series: | Cancer Treatment and Research Communications |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2468294221001854 |
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