Clinical Implications of Immune Checkpoints and the RANK/RANK-L Signaling Pathway in High-Grade Canine Mast Cell Tumors

Clinical Implications of Immune Checkpoints and the RANK/RANK-L Signaling Pathway in High-Grade Canine Mast Cell Tumors

Mast cell tumors (MCTs) are the most common malignant cutaneous tumors in dogs, and they present extremely variable biological behavior. The interaction between RANK, RANK-L, and immune checkpoints is frequently detected in the tumor microenvironment, and, together, they participate in every stage o...

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Bibliographic Details
Main Authors: Noelia C. Talavera Guillén, Andrigo Barboza de Nardi, Felipe Noleto de Paiva, Queila Cristina Dias, Alexandra Pinheiro Fantinatti, Wagner José Fávaro
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Animals
Subjects:
mast cell tumor
immune checkpoints
RANK
RANK-L
dogs
immunotherapy
Online Access:https://www.mdpi.com/2076-2615/13/12/1888

Internet

https://www.mdpi.com/2076-2615/13/12/1888

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