Molecular Studies on the Nephroprotective Potential of <i>Celastrus paniculatus</i> against Lead-Acetate-Induced Nephrotoxicity in Experimental Rats: Role of the PI3K/AKT Signaling Pathway

Molecular Studies on the Nephroprotective Potential of <i>Celastrus paniculatus</i> against Lead-Acetate-Induced Nephrotoxicity in Experimental Rats: Role of the PI3K/AKT Signaling Pathway

Chemicals can induce nephrotoxicity, with damage to different segments of the nephron and deterioration of renal function. Nephrotoxicity due to exposure to a toxin such as carbon tetrachloride, sodium oxalate, or heavy metals is the most common cause of kidney injury. The current study aimed to eva...

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Bibliographic Details
Main Authors: Karunakaran Balaji, Jagadish Vijayakumar, Ponnusamy Kasirajan Sankaran, Sivanesan Senthilkumar, Rajagopalan Vijayaraghavan, Jayaraman Selvaraj, Maria Francis Yuvaraj
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Molecules
Subjects:
<i>Celastrus paniculatus</i>
nephroprotective
electron microscopy
lead acetate
nephrotoxicity
P13K/AKT signaling pathway
Online Access:https://www.mdpi.com/1420-3049/26/21/6647

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https://www.mdpi.com/1420-3049/26/21/6647

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