Reconstructing 3D deformation dynamics for curved epithelial sheet morphogenesis from positional data of sparsely-labeled cells

Quantifying deformation patterns of curved epithelial sheets is challenging owing to imaging difficulties. Here the authors develop a method to obtain a quantitative description of 3D tissue deformation dynamics from a small set of cell positional data and applied it to chick forebrain morphogenesis...

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Bibliographic Details
Main Authors: Yoshihiro Morishita, Ken-ichi Hironaka, Sang-Woo Lee, Takashi Jin, Daisuke Ohtsuka
Format: Article
Language:English
Published: Nature Portfolio 2017-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-017-00023-7