Development of a Prevotella bivia PNA probe and a multiplex approach to detect three relevant species in bacterial vaginosis-associated biofilms

Abstract Bacterial vaginosis (BV) is the most common vaginal infection worldwide. We developed a peptide nucleic acid (PNA) probe targeting Prevotella bivia, a common BV-associated bacteria, and optimized a multiplex approach for detection of Gardnerella spp., P. bivia and Fannyhessea vaginae. Our P...

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Bibliographic Details
Main Authors: Lúcia G. V. Sousa, Carina Almeida, Christina A. Muzny, Nuno Cerca
Format: Article
Language:English
Published: Nature Portfolio 2023-06-01
Series:npj Biofilms and Microbiomes
Online Access:https://doi.org/10.1038/s41522-023-00411-6