Suppression of Pax3–MITF-M Axis Protects from UVB-Induced Skin Pigmentation by Tetrahydroquinoline Carboxamide

Suppression of Pax3–MITF-M Axis Protects from UVB-Induced Skin Pigmentation by Tetrahydroquinoline Carboxamide

Paired box gene 3 (Pax3) and cAMP responsive element-binding protein (CREB) directly interact with the <i>cis</i>-acting elements on the promoter of microphthalmia-associated transcription factor isoform M (MITF-M) for transcriptional activation in the melanogenic process. Tyrosinase (Ty...

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Bibliographic Details
Main Authors: Yong-Pyo Choi, Ga Hyun Kim, Song-Hee Kim, Jongseo Maeng, Heesoon Lee, Sang-Bae Han, Ki Ho Kim, Youngsoo Kim
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:International Journal of Molecular Sciences
Subjects:
tetrahydroquinoline carboxamide
melanin pigmentation
tyrosinase
microphthalmia-associated transcription factor isoform M
paired box gene 3
guinea pig skin
Online Access:https://www.mdpi.com/1422-0067/21/24/9631

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https://www.mdpi.com/1422-0067/21/24/9631

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