Physiological Corticosterone Attenuates gp120-Mediated Microglial Activation and Is Associated with Reduced Anxiety-Like Behavior in gp120-Expressing Mice

Physiological Corticosterone Attenuates gp120-Mediated Microglial Activation and Is Associated with Reduced Anxiety-Like Behavior in gp120-Expressing Mice

Despite the benefits of combinatorial antiretroviral therapies (cART), virotoxic HIV proteins are still detectable within the central nervous system. Approximately half of all cART-treated patients contend with neurological impairments. The mechanisms underlying these effects likely involve virotoxi...

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Bibliographic Details
Main Authors: Emaya M. Moss, Fakhri Mahdi, Charlie J. Worth, Jason J. Paris
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Viruses
Subjects:
affective behavior
glucocorticoids
glycoprotein 120
human immunodeficiency virus
microglia
Online Access:https://www.mdpi.com/1999-4915/15/2/424

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https://www.mdpi.com/1999-4915/15/2/424

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