miR-146a ameliorates liver ischemia/reperfusion injury by suppressing IRAK1 and TRAF6.

A critical role of the Toll-like receptor(TLR) and its downstream molecules, including IL-1 receptor-associated kinase 1(IRAK1) and tumor necrosis factor receptor- associated factor 6(TRAF6), in the pathogenesis of liver ischemia/reperfusion (I/R) injury has been documented. Recently a microRNA, miR...

Full description

Bibliographic Details
Main Authors: Weiwei Jiang, Liangliang Kong, Qingfeng Ni, Yeting Lu, Wenzhou Ding, Guoqing Liu, Liyong Pu, Weibing Tang, Lianbao Kong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0101530&type=printable