Molecular and Structural Analysis of Specific Mutations from Saudi Isolates of SARS-CoV-2 RNA-Dependent RNA Polymerase and their Implications on Protein Structure and Drug–Protein Binding

Molecular and Structural Analysis of Specific Mutations from Saudi Isolates of SARS-CoV-2 RNA-Dependent RNA Polymerase and their Implications on Protein Structure and Drug–Protein Binding

The COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has stressed the global health system to a significant level, which has not only resulted in high morbidity and mortality but also poses a threat for future pandemics. This situation warrants efforts to deve...

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Bibliographic Details
Main Authors: Mubarak A. Alamri, Muhammad Tahir ul Qamar, Alhumaidi B. Alabbas, Safar M. Alqahtani, Manal A. Alossaimi, Sikandar Azam, Muhammad Harris Hashmi, Muhammad Shahid Riaz Rajoka
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Molecules
Subjects:
SARS-CoV-2
COVID-19
mutations
RdRp
molecular dynamics simulation
Online Access:https://www.mdpi.com/1420-3049/27/19/6475

Internet

https://www.mdpi.com/1420-3049/27/19/6475

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