Lpg0393 of Legionella pneumophila is a guanine-nucleotide exchange factor for Rab5, Rab21 and Rab22.

Legionella pneumophila, a human intracellular pathogen, encodes about 290 effector proteins that are translocated into host cells through a secretion machinery. Some of these proteins have been shown to manipulate or subvert cellular processes during infection, but functional roles of a majority of...

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Bibliographic Details
Main Authors: Young-Sik Sohn, Ho-Chul Shin, Wei Sun Park, Jianning Ge, Chan-Hee Kim, Bok Luel Lee, Won Do Heo, Jae U Jung, Daniel John Rigden, Byung-Ha Oh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4379102?pdf=render