Preparation and evaluation of a novel, live, attenuated influenza H1N1 vaccine strain produced by a modified classical reassortment method

Preparation and evaluation of a novel, live, attenuated influenza H1N1 vaccine strain produced by a modified classical reassortment method

Live attenuated influenza vaccine (LAIV)-based Vero cells could provide a better choice to control and prevent influenza virus infections. This study used the human influenza virus A/Yunnan/1/2005Vca(H3N2) (YN/05Vca) as a donor strain. YN/05Vca has a double phenotype of cold adaption (ca) and Vero c...

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Bibliographic Details
Main Authors: Yunfeng Long, Lei Ma, Ze Liu, Shaohui Song, Xingliang Geng, Fan Yang, Qi Guo, Zhuofan Li, Weidong Li, Guoyang Liao
Format: Article
Language:English
Published: Taylor & Francis Group 2018-03-01
Series:Human Vaccines & Immunotherapeutics
Subjects:
classical reassortant
laiv
vaccine assessment
vero cell
Online Access:http://dx.doi.org/10.1080/21645515.2017.1380761

Internet

http://dx.doi.org/10.1080/21645515.2017.1380761

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