Distinct biological ages of organs and systems identified from a multi-omics study

Summary: Biological age (BA) has been proposed to evaluate the aging status instead of chronological age (CA). Our study shows evidence that there might be multiple “clocks” within the whole-body system: systemic aging drivers/clocks overlaid with organ/tissue-specific counterparts. We utilize multi...

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Bibliographic Details
Main Authors: Chao Nie, Yan Li, Rui Li, Yizhen Yan, Detao Zhang, Tao Li, Zhiming Li, Yuzhe Sun, Hefu Zhen, Jiahong Ding, Ziyun Wan, Jianping Gong, Yanfang Shi, Zhibo Huang, Yiran Wu, Kaiye Cai, Yang Zong, Zhen Wang, Rong Wang, Min Jian, Xin Jin, Jian Wang, Huanming Yang, Jing-Dong J. Han, Xiuqing Zhang, Claudio Franceschi, Brian K. Kennedy, Xun Xu
Format: Article
Language:English
Published: Elsevier 2022-03-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124722001863