Phagocytosis of Astaxanthin-Loaded Microparticles Modulates TGF<i>β</i> Production and Intracellular ROS Levels in J774A.1 Macrophages

Phagocytosis of Astaxanthin-Loaded Microparticles Modulates TGF<i>β</i> Production and Intracellular ROS Levels in J774A.1 Macrophages

Radiation-induced fibrosis is a serious long-lasting side effect of radiation therapy. Central to this condition is the role of macrophages that, activated by radiation-induced reactive oxygen species and tissue cell damage, produce pro-inflammatory cytokines, such as transforming growth factor beta...

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Bibliographic Details
Main Authors: Eleonora Binatti, Gianni Zoccatelli, Francesca Zanoni, Giulia Donà, Federica Mainente, Roberto Chignola
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Marine Drugs
Subjects:
astaxanthin
protein microparticles
macrophage targeting
oxidative stress
TGF<i>β</i>
inflammation
Online Access:https://www.mdpi.com/1660-3397/19/3/163

Internet

https://www.mdpi.com/1660-3397/19/3/163

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