Two-color nanoscopy of organelles for extended times with HIDE probes

Two-color nanoscopy of organelles for extended times with HIDE probes

High density environmentally sensitive (HIDE) probes allow for long time-lapse super-resolution imaging of live cells. Here the authors develop a second HIDE probe with a bio-orthogonal labelling strategy to enable two-color nanoscopy of two organelles over extended periods.

Bibliographic Details
Main Authors: Ling Chu, Jonathan Tyson, Juliana E. Shaw, Felix Rivera-Molina, Anthony J. Koleske, Alanna Schepartz, Derek K. Toomre
Format: Article
Language:English
Published: Nature Portfolio 2020-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-17859-1

Internet

https://doi.org/10.1038/s41467-020-17859-1

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