Inferring the demographic history and rate of adaptive substitution in Drosophila.

An important goal of population genetics is to determine the forces that have shaped the pattern of genetic variation in natural populations. We developed a maximum likelihood method that allows us to infer demographic changes and detect recent positive selection (selective sweeps) in populations of...

Full description

Bibliographic Details
Main Authors: Haipeng Li, Wolfgang Stephan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-10-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC1599771?pdf=render