Can N-Methyl-D-Aspartate Receptor Hypofunction in Schizophrenia Be Localized to an Individual Cell Type?

Hypofunction of N-methyl-D-aspartate glutamate receptors (NMDARs), whether caused by endogenous factors like auto-antibodies or mutations, or by pharmacological or genetic manipulations, produces a wide variety of deficits which overlap with—but do not precisely match—the symptom spectrum of schizop...

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Bibliographic Details
Main Authors: Alexei M. Bygrave, Kasyoka Kilonzo, Dimitri M. Kullmann, David M. Bannerman, Dennis Kätzel
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Psychiatry
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Online Access:https://www.frontiersin.org/article/10.3389/fpsyt.2019.00835/full