Synthesis of Functionalized Cannabilactones

A new approach to synthesize cannabilactones using Suzuki cross-coupling reaction followed by one-step demethylation-cyclization is presented. The two key cannabilactone prototypes AM1710 and AM1714 were obtained selectively in high overall yields and in a lesser number of synthetic steps when compa...

Full description

Bibliographic Details
Main Authors: Yingpeng Liu, Thanh C. Ho, Mohammed Baradwan, Maria Pascual Lopez-Alberca, Christos Iliopoulos-Tsoutsouvas, Spyros P. Nikas, Alexandros Makriyannis
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/25/3/684