Continuous infusion of piperacillin‐tazobactam significantly improves target attainment in children with cancer and fever

Continuous infusion of piperacillin‐tazobactam significantly improves target attainment in children with cancer and fever

Abstract Background Children with febrile neutropenia commonly exhibit alterations of pharmacokinetic (PK) parameters, leading to decreased β‐lactam concentrations. Aims This study evaluated piperacillin PK and probability of target attainment (PTA) with continuous infusion of piperacillin‐tazobacta...

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Bibliographic Details
Main Authors: Sabine F. Maarbjerg, Anders Thorsted, Lena E. Friberg, Elisabet I. Nielsen, Mikala Wang, Henrik Schrøder, Birgitte K. Albertsen
Format: Article
Language:English
Published: Wiley 2022-10-01
Series:Cancer Reports
Subjects:
continuous infusion
dose optimization
febrile neutropenia
pharmacokinetics
piperacillin
target attainment
Online Access:https://doi.org/10.1002/cnr2.1585

Internet

https://doi.org/10.1002/cnr2.1585

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