Genetic factors affecting dopaminergic deterioration during the premotor stage of Parkinson disease
Abstract To estimate dopaminergic dysfunction in patients with Parkinson disease (PD) during the premotor stage and to investigate the effect of genetic factors on the trajectories. Using longitudinal dopamine transporter single-photon emission computed tomography data from 367 sporadic PD (sPD), 72...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2021-11-01
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Series: | npj Parkinson's Disease |
Online Access: | https://doi.org/10.1038/s41531-021-00250-2 |