Total Synthesis and Anti-Inflammatory Evaluation of Osajin, Scandenone and Analogues

In this study, the total synthesis of osajin, scandenone and their analogues have been accomplished. The key synthetic steps include aldol/intramolecular iodoetherification/elimination sequence reactions and a Suzuki coupling reaction to assemble the tricyclic core, chemoselective propargylation and...

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Bibliographic Details
Main Authors: Rui Wang, Ran Ma, Ke Feng, Hongchen Lu, Wei Zhao, Hongzhen Jin
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Pharmaceuticals
Subjects:
Online Access:https://www.mdpi.com/1424-8247/17/1/86