Smoking Increases Mortality Risk Among African Americans With Chronic Kidney Disease
Background: Smoking and chronic kidney disease (CKD) have a disproportionately high prevalence among African American (AA) adults, but their impact on mortality among AA adults is not well known. Methods: Given the lack of evidence in published literature on specific factors affecting the relationsh...
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| Format: | Article |
| Language: | English |
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Elsevier
2024-06-01
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| Series: | American Journal of Medicine Open |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2667036424000037 |
| _version_ | 1797287583576752128 |
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| author | Srikanta Banerjee Jagdish Khubchandani W. Sumner Davis |
| author_facet | Srikanta Banerjee Jagdish Khubchandani W. Sumner Davis |
| author_sort | Srikanta Banerjee |
| collection | DOAJ |
| description | Background: Smoking and chronic kidney disease (CKD) have a disproportionately high prevalence among African American (AA) adults, but their impact on mortality among AA adults is not well known. Methods: Given the lack of evidence in published literature on specific factors affecting the relationship between CKD and mortality among AA adults, we examined the influence of smoking on mortality among AA adults with CKD. National Health and Nutrition Examination Survey (NHANES, 1999-2010) data were analyzed with study participants prospectively followed up for mortality analysis through December 31, 2019, using National Death Index (NDI) death certificate records. Results: A total of 6,108 AA adults were included in the study sample, with more than two-fifths (44.9%) being smokers and 6.3% having CKD. AA individuals with CKD had 2.22 (95% CI = 1.38-3.57) times the risk of cardiovascular mortality, but when stratified by smoking, AA individuals with CKD who were current smokers had 3.21 times the risk of cardiovascular mortality. Similarly, in AA with CKD, the risk of all-cause mortality was 3.53 (95% CI = 1.31-9.47), but when stratified by smoking status, AA individuals with CKD who were current smokers had 5.54 times the risk of all-cause mortality. Conclusions: Smoking and CKD are highly prevalent in AA individuals and frequently cooccur, leading to higher rates of mortality. Smoking cessation interventions should be a priority in collaborative care models and interdisciplinary care teams for AA with CKD and current smoker status. |
| first_indexed | 2024-03-07T18:35:27Z |
| format | Article |
| id | doaj.art-916c4e199ca14ea387db61b2450d92c9 |
| institution | Directory Open Access Journal |
| issn | 2667-0364 |
| language | English |
| last_indexed | 2024-03-07T18:35:27Z |
| publishDate | 2024-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | American Journal of Medicine Open |
| spelling | doaj.art-916c4e199ca14ea387db61b2450d92c92024-03-02T04:55:12ZengElsevierAmerican Journal of Medicine Open2667-03642024-06-0111100066Smoking Increases Mortality Risk Among African Americans With Chronic Kidney DiseaseSrikanta Banerjee0Jagdish Khubchandani1W. Sumner Davis2College of Health Sciences, Walden University, Minneapolis, Minn, United States of AmericaCollege of Health, Education, and Social Transformation, New Mexico State University, Las Cruces, N.M., United States of America; Correspondence author: Jagdish Khubchandani, MBBS, PhD, College of Health, Education, and Social Transformation, PO BOX 30001, MSC 3AC, New Mexico State University, Las Cruces, New Mexico, 88003, USA, Phone-001-575-646-4300College of Health Sciences, Walden University, Minneapolis, Minn, United States of AmericaBackground: Smoking and chronic kidney disease (CKD) have a disproportionately high prevalence among African American (AA) adults, but their impact on mortality among AA adults is not well known. Methods: Given the lack of evidence in published literature on specific factors affecting the relationship between CKD and mortality among AA adults, we examined the influence of smoking on mortality among AA adults with CKD. National Health and Nutrition Examination Survey (NHANES, 1999-2010) data were analyzed with study participants prospectively followed up for mortality analysis through December 31, 2019, using National Death Index (NDI) death certificate records. Results: A total of 6,108 AA adults were included in the study sample, with more than two-fifths (44.9%) being smokers and 6.3% having CKD. AA individuals with CKD had 2.22 (95% CI = 1.38-3.57) times the risk of cardiovascular mortality, but when stratified by smoking, AA individuals with CKD who were current smokers had 3.21 times the risk of cardiovascular mortality. Similarly, in AA with CKD, the risk of all-cause mortality was 3.53 (95% CI = 1.31-9.47), but when stratified by smoking status, AA individuals with CKD who were current smokers had 5.54 times the risk of all-cause mortality. Conclusions: Smoking and CKD are highly prevalent in AA individuals and frequently cooccur, leading to higher rates of mortality. Smoking cessation interventions should be a priority in collaborative care models and interdisciplinary care teams for AA with CKD and current smoker status.http://www.sciencedirect.com/science/article/pii/S2667036424000037RaceMortalityKidney diseaseSmokingRisk |
| spellingShingle | Srikanta Banerjee Jagdish Khubchandani W. Sumner Davis Smoking Increases Mortality Risk Among African Americans With Chronic Kidney Disease American Journal of Medicine Open Race Mortality Kidney disease Smoking Risk |
| title | Smoking Increases Mortality Risk Among African Americans With Chronic Kidney Disease |
| title_full | Smoking Increases Mortality Risk Among African Americans With Chronic Kidney Disease |
| title_fullStr | Smoking Increases Mortality Risk Among African Americans With Chronic Kidney Disease |
| title_full_unstemmed | Smoking Increases Mortality Risk Among African Americans With Chronic Kidney Disease |
| title_short | Smoking Increases Mortality Risk Among African Americans With Chronic Kidney Disease |
| title_sort | smoking increases mortality risk among african americans with chronic kidney disease |
| topic | Race Mortality Kidney disease Smoking Risk |
| url | http://www.sciencedirect.com/science/article/pii/S2667036424000037 |
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