Case Report: Novel Compound Heterozygous Variants in TRIOBP Associated With Congenital Deafness in a Chinese Family

Case Report: Novel Compound Heterozygous Variants in TRIOBP Associated With Congenital Deafness in a Chinese Family

Autosomal recessive non-syndromic deafness-28 (DFNB28) is characterized by prelingual, profound sensorineural hearing loss (HL). The disease is related to variants of the TRIOBP gene. TRIO and F-actin binding protein (TRIOBP) plays crucial roles in modulating the assembly of the actin cytoskeleton a...

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Bibliographic Details
Main Authors: Cong Zhou, Yuanyuan Xiao, Hanbing Xie, Jing Wang, Shanling Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Genetics
Subjects:
TRIOBP
DFNB28
variation
hearing loss
next generation sequencing
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.766973/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2021.766973/full

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