Glycomimetic antagonists of BC2L-C lectin: insights from molecular dynamics simulations

Glycomimetic antagonists of BC2L-C lectin: insights from molecular dynamics simulations

Opportunistic infections from multidrug-resistant pathogens such as Burkholderia cenocepacia are a threatening risk for hospital-bound patients suffering from immunocompromised conditions or cystic fibrosis. B. cenocepacia BC2L-C lectin has been linked to bacterial adhesion and biofilm formation, th...

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Bibliographic Details
Main Authors: Giulia Antonini, Monica Civera, Kanhaya Lal, Sarah Mazzotta, Annabelle Varrot, Anna Bernardi, Laura Belvisi
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Molecular Biosciences
Subjects:
lectins
glycomimetics
molecular dynamics simulations
C-fucosides
fucosyl amides
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2023.1201630/full

Internet

https://www.frontiersin.org/articles/10.3389/fmolb.2023.1201630/full

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