An E2F5-TFDP1-BRG1 Complex Mediates Transcriptional Activation of MYCN in Hepatocytes

An E2F5-TFDP1-BRG1 Complex Mediates Transcriptional Activation of MYCN in Hepatocytes

Liver regeneration is characterized by cell cycle reentrance of hepatocytes. N-Myc, encoded by MYCN, is a member of the Myc family of transcription factors. Elevation of MYCN expression has been noted in the course of liver regeneration whereas the underlying mechanism remains unclear. Here we descr...

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Bibliographic Details
Main Authors: Zhiwen Fan, Ming Kong, Xiulian Miao, Yan Guo, Haozhen Ren, Jinglin Wang, Shuai Wang, Ning Tang, Longcheng Shang, Zhengyi Zhu, Hanyi Liu, Wei Zhu, Xiaolei Shi
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
transcriptional regulation
hepatocyte
liver regeneration
epigenetics
chromatin remodeling protein
proliferation
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.742319/full

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https://www.frontiersin.org/articles/10.3389/fcell.2021.742319/full

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