MVA-based vaccines are protective against lethal eastern equine encephalitis virus aerosol challenge in cynomolgus macaques

MVA-based vaccines are protective against lethal eastern equine encephalitis virus aerosol challenge in cynomolgus macaques

Abstract MVA-based monovalent eastern equine encephalitis virus (MVA-BN-EEEV) and multivalent western, eastern, and Venezuelan equine encephalitis virus (MVA-BN-WEV) vaccines were evaluated in the cynomolgus macaque aerosol model of EEEV infection. Macaques vaccinated with two doses of 5 × 108 infec...

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Bibliographic Details
Main Authors: Brandon J. Beddingfield, Kenneth S. Plante, Jessica A. Plante, Scott C. Weaver, Sarah Bose, Clara Krzykwa, Nicole Chirichella, Rachel K. Redmann, Stephanie Z. Seiler, Jason Dufour, Robert V. Blair, Kathrin Endt, Ariane Volkmann, Nicholas J. Maness, Chad J. Roy
Format: Article
Language:English
Published: Nature Portfolio 2024-02-01
Series:npj Vaccines
Online Access:https://doi.org/10.1038/s41541-024-00842-y

Internet

https://doi.org/10.1038/s41541-024-00842-y

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