Molecular determinants and dynamics of hepatitis C virus secretion.

The current model of hepatitis C virus (HCV) production involves the assembly of virions on or near the surface of lipid droplets, envelopment at the ER in association with components of VLDL synthesis, and egress via the secretory pathway. However, the cellular requirements for and a mechanistic un...

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Bibliographic Details
Main Authors: Kelly E Coller, Nicholas S Heaton, Kristi L Berger, Jacob D Cooper, Jessica L Saunders, Glenn Randall
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3252379?pdf=render