Novel and multiple targets for chimeric antigen receptor-based therapies in lymphoma

Chimeric antigen receptor (CAR) T-cell therapy targeting CD19 in B-cell non-Hodgkin lymphoma (NHL) validates the utility of CAR-based therapy for lymphomatous malignancies. Despite the success, treatment failure due to CD19 antigen loss, mutation, or down-regulation remains the main obstacle to cure...

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Podrobná bibliografie
Hlavní autoři: Yifan Pang, Nilanjan Ghosh
Médium: Článek
Jazyk:English
Vydáno: Frontiers Media S.A. 2024-04-01
Edice:Frontiers in Oncology
Témata:
On-line přístup:https://www.frontiersin.org/articles/10.3389/fonc.2024.1396395/full