Myeloperoxidase-deficient mice exposed to Zymosan exhibit severe neutrophilia and anemia with enhanced granulopoiesis and reduced erythropoiesis, accompanied by pulmonary inflammation

We previously reported that myeloperoxidase-deficient (MPO-/-) mice develop more severe neutrophil-rich lung inflammation than wild-type mice following intranasal Zymosan administration. Interestingly, we found that these mutant mice with severe lung inflammation also displayed pronounced neutrophil...

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Bibliographic Details
Main Authors: Misaki Yoshikawa, Yuki Sato, Mayu Sasaki, Yasuaki Aratani
Format: Article
Language:English
Published: Elsevier 2024-09-01
Series:Immunobiology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0171298524000615