Adaptive optics in single objective inclined light sheet microscopy enables three-dimensional localization microscopy in adult Drosophila brains

Adaptive optics in single objective inclined light sheet microscopy enables three-dimensional localization microscopy in adult Drosophila brains

Single-molecule localization microscopy (SMLM) enables the high-resolution visualization of organelle structures and the precise localization of individual proteins. However, the expected resolution is not achieved in tissue as the imaging conditions deteriorate. Sample-induced aberrations distort t...

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Bibliographic Details
Main Authors: Shih-Te Hung, Arnau Llobet Rosell, Daphne Jurriens, Marijn Siemons, Oleg Soloviev, Lukas C. Kapitein, Kristin Grußmayer, Lukas J. Neukomm, Michel Verhaegen, Carlas Smith
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Neuroscience
Subjects:
Super-resolution Microscopy
localization microscopy
adaptive optics
Drosophila
brain
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2022.954949/full

Internet

https://www.frontiersin.org/articles/10.3389/fnins.2022.954949/full

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