MYC is a regulator of androgen receptor inhibition-induced metabolic requirements in prostate cancer

MYC is a regulator of androgen receptor inhibition-induced metabolic requirements in prostate cancer

Summary: Advanced prostate cancers are treated with therapies targeting the androgen receptor (AR) signaling pathway. While many tumors initially respond to AR inhibition, nearly all develop resistance. It is critical to understand how prostate tumor cells respond to AR inhibition in order to exploi...

書誌詳細
主要な著者:	Preston D. Crowell, Jenna M. Giafaglione, Anthony E. Jones, Nicholas M. Nunley, Takao Hashimoto, Amelie M.L. Delcourt, Anton Petcherski, Raag Agrawal, Matthew J. Bernard, Johnny A. Diaz, Kylie Y. Heering, Rong Rong Huang, Jin-Yih Low, Nedas Matulionis, Nora M. Navone, Huihui Ye, Amina Zoubeidi, Heather R. Christofk, Matthew B. Rettig, Robert E. Reiter, Michael C. Haffner, Paul C. Boutros, Orian S. Shirihai, Ajit S. Divakaruni, Andrew S. Goldstein
フォーマット:	論文
言語:	English
出版事項:	Elsevier 2023-10-01
シリーズ:	Cell Reports
主題:	CP: Cancer CP: Metabolism
オンライン･アクセス:	http://www.sciencedirect.com/science/article/pii/S2211124723012330

類似資料

ZFP36-mediated mRNA decay regulates metabolism
著者:: Andrew C. Cicchetto, 等
出版事項: (2023-05-01)

Uptake of tumor-derived microparticles induces metabolic reprogramming of macrophages in the early metastatic lung
著者:: Kelly Kersten, 等
出版事項: (2023-06-01)

Endothelial Jagged1 levels and distribution are post-transcriptionally controlled by ZFP36 decay proteins
著者:: Hannah L. Sunshine, 等
出版事項: (2024-01-01)

AAV5-mediated manipulation of insulin expression in choroid plexus has long-term metabolic and behavioral consequences
著者:: Caio Henrique Mazucanti, 等
出版事項: (2023-08-01)

Comparative transcriptomic profiling reveals a role for Olig1 in promoting axon regeneration
著者:: Xiu-Qing Fu, 等
出版事項: (2024-07-01)

Genetically modified IL2 bone-marrow-derived myeloid cells reprogram the glioma immunosuppressive tumor microenvironment
著者:: Alessandro Canella, 等
出版事項: (2023-08-01)

Bordetella spp. block eosinophil recruitment to suppress the generation of early mucosal protection
著者:: Nicholas J. First, 等
出版事項: (2023-11-01)

Five autism-associated transcriptional regulators target shared loci proximal to brain-expressed genes
著者:: Siavash Fazel Darbandi, 等
出版事項: (2024-06-01)

Hexokinase 2-mediated metabolic stress and inflammation burden of liver macrophages via histone lactylation in MASLD
著者:: Jinyang Li, 等
出版事項: (2025-03-01)

Comparing neoantigen cancer vaccines and immune checkpoint therapy unveils an effective vaccine and anti-TREM2 macrophage-targeting dual therapy
著者:: Sunita Keshari, 等
出版事項: (2024-11-01)

The HLA-II immunopeptidome of SARS-CoV-2
著者:: Shira Weingarten-Gabbay, 等
出版事項: (2024-01-01)

IL-37 dampens immunosuppressive functions of MDSCs via metabolic reprogramming in the tumor microenvironment
著者:: Yu Mei, 等
出版事項: (2024-03-01)

Parent-of-origin-specific DNA replication timing is confined to large imprinted regions
著者:: Matthew M. Edwards, 等
出版事項: (2024-09-01)

A versatile pumpless multi-channel fluidics system for maintenance and real-time functional assessment of tissue and cells
著者:: Varun Kamat, 等
出版事項: (2023-11-01)

The genome of Stephania japonica provides insights into the biosynthesis of cepharanthine
著者:: Zhuo Liu, 等
出版事項: (2024-03-01)

“Forcing” new interpretations of molecular tension sensor studies
著者:: Matthew R. Pawlak, 等
出版事項: (2024-07-01)

Cells use multiple mechanisms for cell-cycle arrest upon withdrawal of individual amino acids
著者:: Yao Rong, 等
出版事項: (2023-12-01)

Tumor eradication by hetIL-15 locoregional therapy correlates with an induced intratumoral CD103intCD11b+ dendritic cell population
著者:: Dimitris Stellas, 等
出版事項: (2023-05-01)

A microRNA-regulated transcriptional state defines intratumoral CD8+ T cells that respond to immunotherapy
著者:: William W. Tang, 等
出版事項: (2025-02-01)

PANAMA-enabled high-sensitivity dual nanoflow LC-MS metabolomics and proteomics analysis
著者:: Weiwei Lin, 等
出版事項: (2024-07-01)

XRN1 deletion induces PKR-dependent cell lethality in interferon-activated cancer cells
著者:: Tao Zou, 等
出版事項: (2024-02-01)

ASCL1 is activated downstream of the ROR2/CREB signaling pathway to support lineage plasticity in prostate cancer
著者:: Nakisa Tabrizian, 等
出版事項: (2023-08-01)

A reverse transcriptase controls prophage genome reduction to promote phage dissemination in Pseudomonas aeruginosa biofilms
著者:: Yunxue Guo, 等
出版事項: (2024-11-01)

Angiotensin AT1A receptor signal switching in Agouti-related peptide neurons mediates metabolic rate adaptation during obesity
著者:: Kirthikaa Balapattabi, 等
出版事項: (2023-08-01)

Distinct myeloid population phenotypes dependent on TREM2 expression levels shape the pathology of traumatic versus demyelinating CNS disorders
著者:: Han Gao, 等
出版事項: (2023-06-01)

High-throughput identification of calcium-regulated proteins across diverse proteomes
著者:: Timothy M. Locke, 等
出版事項: (2024-11-01)

The genomic and evolutionary landscapes of anaplastic thyroid carcinoma
著者:: Peter Y.F. Zeng, 等
出版事項: (2024-03-01)

Smooth muscle cell-derived Cxcl12 directs macrophage accrual and sympathetic innervation to control thermogenic adipose tissue
著者:: Derek Lee, 等
出版事項: (2024-05-01)

Clostridioides difficile toxin B subverts germinal center and antibody recall responses by stimulating a drug-treatable CXCR4-dependent mechanism
著者:: Kaylee M. Norman, 等
出版事項: (2024-05-01)

JAML immunotherapy targets recently activated tumor-infiltrating CD8+ T cells
著者:: Simon Eschweiler, 等
出版事項: (2023-02-01)

CD115+ monocytes protect microbially experienced mice against E. coli-induced sepsis
著者:: Matthew D. Martin, 等
出版事項: (2023-11-01)

Iron overload in hypothalamic AgRP neurons contributes to obesity and related metabolic disorders
著者:: Yi Zhang, 等
出版事項: (2024-03-01)

Epigenomic signatures of sarcomatoid differentiation to guide the treatment of renal cell carcinoma
著者:: Talal El Zarif, 等
出版事項: (2024-06-01)

Acute and persistent responses after H5N1 vaccination in humans
著者:: Richard Apps, 等
出版事項: (2024-09-01)

FAM193A is a positive regulator of p53 activity
著者:: Maria M. Szwarc, 等
出版事項: (2023-03-01)

Insulin receptor signaling engages bladder urothelial defenses that limit urinary tract infection
著者:: Laura Schwartz, 等
出版事項: (2024-04-01)

Transcriptional programming mediated by the histone demethylase KDM5C regulates dendritic cell population heterogeneity and function
著者:: Hannah Guak, 等
出版事項: (2024-08-01)

Experimental bacterial dysbiosis with consequent immune alterations increase intrarectal SIV acquisition susceptibility
著者:: Alexandra M. Ortiz, 等
出版事項: (2023-01-01)

Phosphoprotein dynamics of interacting T cells and tumor cells by HySic
著者:: Sofía Ibáñez-Molero, 等
出版事項: (2024-01-01)

An ERK5-PFKFB3 axis regulates glycolysis and represents a therapeutic vulnerability in pediatric diffuse midline glioma
著者:: Stephanie M. Casillo, 等
出版事項: (2024-01-01)