An IFNT/FOXO1/PTGS2 axis regulates prostaglandin F2α synthesis in goat uterus during early pregnancy

An IFNT/FOXO1/PTGS2 axis regulates prostaglandin F2α synthesis in goat uterus during early pregnancy

ABSTRACT: In ruminants, IFN-tau (IFNT) regulates the production of prostaglandins (PG) in the endometrium, which is crucial for conceptus adhesion. However, the related molecular regulatory mechanisms remain unclear. Forkhead box O1 (FOXO1), a member of the FOXO subfamily of transcription factors, i...

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Bibliographic Details
Main Authors: Li-Ge Bu, Bo Wang, Ting-Yue Li, Ya Sun, Li-Li Kong, Zhen-Ao Zhao, Shi-Jie Li, Nai-Zheng Ding, Hua Ni
Format: Article
Language:English
Published: Elsevier 2023-11-01
Series:Journal of Dairy Science
Subjects:
FOXO1
PTGS2
prostaglandins
interferon-tau
goat uterus
early pregnancy
Online Access:http://www.sciencedirect.com/science/article/pii/S0022030223003120

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http://www.sciencedirect.com/science/article/pii/S0022030223003120

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