Genomic alterations in KMT2 family predict outcome of immune checkpoint therapy in multiple cancers
Abstract Immune checkpoint therapy (ICT) can produce durable antitumor responses in various cancer types; however, the responses are not universal, and the predictive biomarkers are urgently needed. Growing evidence points to a link between epigenetic regulation and anti-tumor immunity, while clinic...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
BMC
2021-03-01
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Series: | Journal of Hematology & Oncology |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13045-021-01050-0 |