Hymenaea rubriflora Ducke stem bark extract has vasorelaxant and contractile inhibition capacity

Hymenaea rubriflora Ducke stem bark extract has vasorelaxant and contractile inhibition capacity

Abstract We investigated the vasodilatory effects of Hymenaea rubriflora Ducke stem bark extract (HR- HAc). Vascular reactivity of the aortic rings of Wistar rats was tested by in vitro cumulative doses (0.1 - 729 μg/mL). Rats (n=5) were treated with 25 (G25), 50 (G50) and 100 (G100) mg/ kg of HR-HA...

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Main Authors: Keyth Sulamitta de Lima Guimarães, Luciana Tavares Toscano, Bagnólia Araújo Costa, Iara Leão Luna de Souza, Isabelle de Lima Brito Polari, Ivyne Oliveira Araújo Wanderley, Manoel Miranda Neto, Bárbara Cavalcanti Barros, Rubens Teixeira de Queiroz, Ângela Maria Tribuzy de Magalhães Cordeiro, Maria da Conceição Rodrigues Gonçalves, Lydiane de Lima Tavares Toscano, Alexandre Sérgio Silva
Format: Article
Language:English
Published: Universidade de São Paulo 2024-02-01
Series:Brazilian Journal of Pharmaceutical Sciences
Subjects:
Antioxidant
Aorta
Hymenaea rubriflora ducke
Nitric oxide
Vasorelaxation
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502024000100308&lng=en&tlng=en

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