Plausibility of Daphnia magna as an alternative experimental model to evaluate effects on eicosanoid synthesis

Eicosanoids play important roles in inflammation, allergy, fever, and immune responses. In the eicosanoid pathway, cyclooxygenase (COX) catalyzes the conversion of arachidonic acid to prostaglandins and is a crucial target of nonsteroidal anti-inflammatory drugs (NSAIDs). Thus, toxicological studies...

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Bibliographic Details
Main Authors: Sangwoo Lee, Gun Tae Jung, Mina Cho, Jae Won Lee, Kojo Eghan, Jieon Lee, Seokjoo Yoon, Kwang Pyo Kim, Woo-Keun Kim
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651323006231