Investigation of thrombin generation assay to predict vaso-occlusive crisis in adulthood with sickle cell disease

Investigation of thrombin generation assay to predict vaso-occlusive crisis in adulthood with sickle cell disease

IntroductionSickle cell disease (SCD) is an inherited hemoglobinopathy disorder. The main consequence is synthesis of hemoglobin S leading to chronic hemolysis associated with morbidity. The aim of this study was to investigate Thrombin Generation Assay (TGA) to assess hypercoagulability in SCD and...

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Bibliographic Details
Main Authors: Guillaume Feugray, Fiston Kasonga, Maximilien Grall, Cécile Dumesnil, Ygal Benhamou, Valery Brunel, Véronique Le Cam Duchez, Agnès Lahary, Paul Billoir
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
thrombin generation assay
hypercoagulability
hemoglobinopathy
sickle cell disease
vaso-occlusive crisis
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2022.883812/full

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https://www.frontiersin.org/articles/10.3389/fcvm.2022.883812/full

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